| Date | Location | Result | |
| 3/14/06 | St. Joseph's College - Rensselaer, IN | Southern Illinois-Edwardsville 64, University of Southern Indiana 60 | Box score |
| 3/12/06 | St. Joseph's College - Rensselaer, IN | University of Southern Indiana 81, St. Joseph's College 78 | Box score |
| 3/11/06 | St. Joseph College - Rensselaer, IN | University of Southern Indiana 78, Drury University 58 | Box score |
| 3/3/06 | Evansville, IN/Roberts Stadium | Saint Joseph's 80, Southern Indiana 71 | Box score |
| 2/25/06 | Evansville, IN/PAC | Southern Indiana 80, Missouri-St. Louis 52 | Box score |
| 2/23/06 | Evansville, IN/PAC | Southern Indiana 97, Missouri-Rolla 60 | Box score |
| 2/16/06 | Edwardsville, Ill./Vadalabene Center | SIU Edwardsville 67, Southern Indiana 63 | Box score |
| 2/16/06 | Pepsi Arena; Quincy, Illinois | Quincy University 76, Southern Indiana 71 | Box score |
| 2/11/06 | Evansville, IN/PAC | Southern Indiana 74, Rockhurst 59 | Box score |
| 2/9/06 | Evansville, IN/PAC | Drury University 83, Southern Indiana 82 | Box score |
| 2/4/06 | Owensboro Sportscenter, Owensboro, Ky. | Southern Indiana 74, Kentucky Wesleyan 58 | Box score |
| 1/28/06 | Evansville, IN/PAC | Southern Indiana 98, Saint Joseph's 67 | Box score |
| 1/26/06 | Evansville, IN/PAC | Southern Indiana 95, Indianapolis 70 | Box score |
| 01/21/06 | Rockhurst University | Southern Indiana 87, Rockhurst 64 | Box score |
| 1/19/06 | Springfield, Missouri/Weiser Gym | Southern Indiana 69, Drury University 65 | Box score |
| 1/14/06 | Evansville, IN/PAC | SIU Edwardsville 78, Southern Indiana 77 | Box score |
| 1/12/06 | Evansville, IN/PAC | Southern Indiana 82, Quincy 70 | Box score |
| 1/7/06 | Highland Heights, Ky. | Southern Indiana 75, Northern Kentucky 56 | Box score |
| 1/5/06 | Louisville, Ky. (Knights Hall) | Southern Indiana 95, Bellarmine University 76 | Box score |
| 1/2/06 | Evansville, IN/PAC | Southern Indiana 114, Oakland City 56 | Box score |
| 12/31/05 | Evansville, IN/PAC | Southern Indiana 110, Lees-McRae 69 | Box score |
| 12/21/05 | Nicoson Hall, Indianapolis, Ind. | Southern Indiana 78, Wayne State 59 | Box score |
| 12/20/05 | Nicoson Hall, Indianapolis, Ind. | Southern Indiana 88, Ferris State 81 | Box score |
| 12/17/05 | Evansville, IN/PAC | Southern Indiana 88, Bryan 53 | Box score |
| 12/10/05 | Evansville, IN/PAC | Southern Indiana 60, Lewis 49 | Box score |
| 12/8/05 | Evansville, IN/PAC | Southern Indiana 83, Wisconsin-Parkside 61 | Box score |
| 12/03/05 | St. Louis, Mo. (Mark Twain Building) | Missouri-St. Louis 87, Southern Indiana 83 | Box score |
| 12/1/05 | Rolla, Mo. (Bullman Multi-Purpose Bldg.) | Southern Indiana 70, Missouri-Rolla 55 | Box score |
| 11/26/05 | Evansville, IN/PAC | Southern Indiana 94, Central State 68 | Box score |
| 11/26/05 | Evansville, IN | Bellarmine 101, Glenville State 80 | Box score |
| 11/25/05 | Evansville, IN/PAC | Southern Indiana 107, Glenville State 69 | Box score |
| 11/25/05 | Evansville, IN | Bellarmine 79, Central State 60 | Box score |
| 11/22/05 | Evansville, IN/PAC | Southern Indiana 92, Robert Morris 43 | Box score |
| 11/13/05 | Disney Wide World of Sports | SOUTHERN INDIANA 90, COLUMBUS ST. UNIV. 86 | Box score |
| 11/12/05 | Disney Wide World of Sports | SOUTHERN INDIANA 76, UNIV.OF NEBRASKA OMAHA 71 | Box score |
| 11/11/05 | Milk House, Lake Buena Vista, Fla. | SOUTHERN INDIANA 88, CALDWELL COLLEGE 71 | Box score |