University of Southern Indiana

Oral Anticoagulation Therapy Program

Coming in August 2018

Description of Program
Oral anticoagulation therapy is associated with an increased risk for adverse drug events leading to emergency department visits and readmission to acute care facilities.  Since the 1960s warfarin was utilized to improve patient outcomes. Despite the challenges associated with its use, warfarin remains a foundational drug for patients.  Starting in 2010, the direct oral anticoagulants represent other choices for patients. Health care professionals who care for patients requiring these medications must remain knowledgeable on the current guidelines and best practices to improve patient outcomes.

Who should enroll in this program?
This program is designed for English-speaking health professionals (nurses, advanced practice nurses, pharmacists, and physicians) involved in the management of patients requiring oral anticoagulation therapy.

Program Content
A textbook is not required for this program.

Learning Outcome
The learning outcome of this program is to enable the learner to distinguish the differences and similarities between the oral anticoagulant drugs and employ the current therapeutic guidelines and best practices in managing anticoagulation therapy.

Program Objectives
At the conclusion of this program, the participant will be able to:

1. Define the terms platelet adhesion, platelet activation, and platelet aggregation.
2.  Describe the general process of hemostasis, including the sequence of the three stages that prevent blood loss.
3.  Explain the role of the vascular endothelium, platelets, circulating clotting factors, endogenous anticoagulants, and thrombolytic proteins in the coagulation process.
4. Briefly describe the series of events that occur in the extrinsic pathway, the intrinsic (contact) pathway, and the common pathway.
5. Define the major functions of thrombin and fibrin in the clotting cascade.
6. Define how activation proteins (proteins C and S) are produced and the role of vitamin K in their production.
7. Identify and discuss the mechanisms, pharmacokinetics, pharmacodynamics, dosing, monitoring, adverse effects, and management of warfarin.
8. Compare and contrast the pharmacokinetics, pharmacodynamics, dosing, monitoring, adverse effects and management of the direct acting oral anticoagulants.
9. Identify and discuss the role of antithrombotic and thrombolytic drugs in valvular disease, atrial fibrillation, and stroke.
10. Apply the current clinical guidelines when choosing the appropriate anticoagulation therapy for patients with VTE and atrial fibrillation.

Delivery of the Content
The learner will log into the program via the internet and work independently through the modules. The independent study provides an opportunity to learn while in the comfort of your own home and office.  Program staff are available during business hours by phone or email to assist participants with technical issues or concerns.  Questions regarding content can be directed to the contributors of the content. After the learner works through the content, she/he will complete the case-based comprehensive exam.   

Note: Many businesses, especially government agencies or health institutions, utilize security firewalls.  Access to web links within program and communication from the instructor, or other students may be blocked. We recommend not using your work email address for this course.

Contact hours
10 contact hours

Successful completion of this program does not guarantee expertise in the content. Clinical experience and judgment coupled with an understanding of the content are necessary to attain competency. Achieving certification is a means to demonstrate competency.

Criteria for Successful Completion

  • Submit registration and payment.
  • A certificate for contact hours will be awarded with the completion of case-study analysis and submission of program evaluation. Following review of the content, the learner will apply the content to patient case studies to demonstrate problem solving and decision- making strategies. The certificates will be sent via email within approximately 30 days following the completion of the program.

Faculty Name and Credentials

We strive to provide interprofessional education by utilizing a variety of content experts, instructors, contributors, and reviewers.

Jane Swartz DNP, RN, ACNS-BC

Holly Jahn PharmD, CACP

Colleen Walsh, DNP, RN, ONC, ONP-C, CNS, ACNP-BC

Conflict of Interest Statement

There is no conflict of interest for anyone in a position to control content for this activity.

Expiration date: August 1, 2020. 

Accreditation with Distinction

The University of Southern Indiana College of Nursing and Health Professions is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation. USI was recognized as accredited with distinction through November 30, 2018.

to send us your ideas for program content.

Contact Dr. M. Jane Swartz


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